【用戶】GE
【年級】大一下
【評論內容】(A)ramelteon的作用機制selective MT1 和 MT2 agonist(B)melatonin是由松果體(pineal gland)分泌 (C)ramelteon和fluvoxamine (CYP1A2抑制劑)合用,會使ramelteon的血漿峰濃度增加50倍以上 (D)ramelteon的副作用為疲勞、頭暈和影響內分泌
【用戶】GE
【年級】大一下
【評論內容】(A)ramelteon的作用機制selective MT1 和 MT2 agonist(B)melatonin是由松果體(pineal gland)分泌 (C)ramelteon和fluvoxamine (CYP1A2抑制劑)合用,會使ramelteon的血漿峰濃度增加50倍以上 (D)ramelteon的副作用為疲勞、頭暈和影響內分泌
【用戶】如果詳解被鎖找 北醫王瑞賢
【年級】高一上
【評論內容】【解題】(A)Ramelteon為選擇性MT1、MT2 Agonist(B)Melatonin為松果腺(pineal gland)分泌的serotonin衍生物(C)Melatonin為CYP1A2代謝,Fluvoxamine會抑制CYP1A2,故不併用(D)Melatonin的副作用:疲勞、暈眩、頭痛【附上原文】P.287 Melatonin pharmacology box(A) Ramelteon is a selective MT1 and MT2 agonist that is approved for the medical treatment of insomniaP.1143:(B)Melatonin, a serotonin derivative produced by the pineal gland (D)Although melatonin is associated with few adverse effects, some next-day drowsiness has been reported as well as fatigue, dizziness, headache, and irritabilityP.1144(C) Melatoni...