【Chris】評論

End product of phagocytosing an RBC: unconjugated bilirubin.  When the RBC is broken down, you have hemoglobin, and there is an enzyme that splits heme from globin and the globin is broken into aa’s and therefore goes to the aa pool. Then, takes the heme, splits it open, and saves the Fe. Now you have protoporphyrin, and spit it out; end result is unconjugated bilirubin in the macrophage within the spleen.  Then, the macrophage spits out the unconjugated bilirubin into blood stream (which is insoluble b/c it’s unconjugated).   The unconjugated bilirubin then binds albumin and goes to the ...