問題詳情

65.有關levothyroxine用於治療甲狀腺功能低下的劑量,下列敘述何者正確?

(A)一般成人建議劑量為1.6~1.7 μg/kg/day
(B)孕婦所需劑量較一般建議劑量調降30~50%
(C)老年人所需劑量較一般建議劑量增加10~20%
(D)3~6 months嬰兒建議劑量為5~6 μg/kg/day

參考答案

答案:A

統計:A:535,B:195,C:93,D:110,E:0

難度:適中

用户評論

IG:Pharmabook】評論

各選項解題 + 10th koda & kimble p.1112 & TABLE 52-4(B)、(C)、(D)應改成(B)孕婦所需劑量較一般建議劑量調高30~50%(C)老年人的劑量要降低!50mcg/day (半顆開始),有CHD病史者,initial dose更應該是從25mcg/day (四分之一顆)開始。大概每三到六個星期緩慢增加劑量,一次劑量可增加25mcg/day(四分之一顆)(D)3~6 months嬰兒建議劑量為10-15  μg/kg/day(A)The signs and symptoms of hypothyroidism can be easily corrected in most patients by the administration of l-thyroxine on an empty stomach at an oral replacement dosage of 1.6 to 1.7 mcg/kg/day(B)Most women with hypothyroidism who are taking oral thyroid hormones before pregnancy, similarto S.C., will require an increase in their dosage by about 30% to 50% throughout their pregnancy