【用戶】aranzl
【年級】高一上
【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C
【用戶】Chelsea Chen
【年級】高二下
【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...
【用戶】aranzl
【年級】高一上
【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C
【用戶】Chelsea Chen
【年級】高二下
【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...
【用戶】aranzl
【年級】高一上
【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C
【用戶】Chelsea Chen
【年級】高二下
【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...