問題詳情

65.併用digoxin與erythromycin產生藥品交互作用時,最主要的原因為何?
(A)改變腸胃道的pH值
(B)增加藥品的代謝
(C)競爭藥品受體的結合點
(D)改變腸胃道內細菌的含量

參考答案

答案:D
難度:簡單0.701396
統計:A(34),B(64),C(60),D(653),E(0)

用户評論

【用戶】蘇莉琄

【年級】國三上

【評論內容】會改變腸道內菌叢有cephalosporin、tetracycline

【用戶】aranzl

【年級】高一上

【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C 

【用戶】腦洞爆炸

【年級】大三上

【評論內容】

【用戶】Chelsea Chen

【年級】高二下

【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...

【用戶】蘇莉琄

【年級】國三上

【評論內容】會改變腸道內菌叢有cephalos.....看完整詳解

【用戶】aranzl

【年級】高一上

【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C 

【用戶】Chelsea Chen

【年級】高二下

【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...

【用戶】aranzl

【年級】高一上

【評論內容】65.Erythromycin與下列藥品均有交互作用,何者之機轉與其他三者不相同? (A)carbamazepine (B)cyclosporine (C)digoxin (D)tacrolimus專技 - 調劑學與臨床藥學- 103 年 - 103-1-藥師-調劑學與臨床藥學#14227答案:C 

【用戶】Chelsea Chen

【年級】高二下

【評論內容】兩個機轉:1. macrolide 抑制p-gp,使digoxin 無法排除而累積2. macrolide 清除可以代謝digoxin 的細菌,使更多的digoxin 被吸收Macrolide inhibition of P-glycoprotein (P-gp) mediated transport of cardiac glycosides could theoretically lead to increases in glycoside bioavailability and/or decreases in renal clearance. Several macrolides inhibit P-glycoprotein (P-gp) mediated transport of digoxin and digitoxin to some extent in vitro with telithromycin showing the greatest inhibitory potency, followed by clarithromycin, followed by azithromycin and erythromycin.A second theory, which has not been the su...