【北醫王瑞賢國考統整衝刺講義】評論

11th applied p.1243  Medication overuse headache 章節(A)機轉：神經結構hypometabolism→神經化學物質改變(orexinA,corticotropin-releasing factor)→改變受體表現、神經胜肽(CGRP↑)The pathophysiology of medicationoveruse headache is multidimensional and is related to hypometabolism inneuroanatomic structures, neurochemical alterations (e.g., orexinA,corticotropin-releasing factor), and alterations in receptor expression andneuropeptide levels (e.g., increase in CGRP)(B)為過度使用Triptans、ergot、opioid analgesics(定義：處方藥：>10天/月 ; OTC：>15天/月)Medication overuse is defined as the...

【王瑞賢國考統整衝刺講義】評論

11th applied p.1243  ...

【神奇地瓜泥】評論

Uptodate的資料供參病因: Genetic predisposition: 本身已經有頭痛症狀的人Central sensitization: (e.g. triptans can downregulate serotonin receptors (5-HT 1B and 5-HT 1D))        chronic morphine increased expression of calcitonin gene-related peptide in primary afferent neuronsBiobehavioral factors: 習慣使用止痛藥診斷:1: 每個月頭痛 ≥ 15 天 (with a pre-existing headache disorder)2. >3 個月過度使用止痛藥治療頭痛－每個月 ≥ 10 天: ergotamines, triptans, opioids, 或是 合併藥物 (包含acetaminophen, aspirin, NSAID)－每個月 ≥ 15 天: acetaminophen, aspirin, NSAID3. 沒有其他 ICHD-3 的頭痛...

【祝好運！一切順利~】評論

77.彭小姐，30歲，偏頭痛病史多★。...