【Bryan】評論

Drug Classes → Metabolic Agents → Antidiabetic Agents → Meglitinides: repaglinide Meglinitides work by stimulating the pancreas to release insulin in response to a meal. It closes ATP-dependent potassium channels in functioning pancreatic beta cells. This blockade of potassium channels depolarizes the beta cells, which leads to opening of calcium channels resulting in influx of calcium. Increased intracellular calcium induces insulin secretion.Meglitinides are used in the treatment of Type 2 diabetes...