問題詳情

42 下列何藥在老人的療效會降低?
(A)Isoproterenol
(B)Levodopa
(C)Pentazocine
(D)Metoclopramide

參考答案

答案:A
難度:困難0.205882
統計:A(7),B(16),C(8),D(3),E(0)

用户評論

【用戶】Bryan

【年級】國三上

【評論內容】Isoprenaline (INN) or isoproterenol (USAN, trade names Medihaler-Iso and Isuprel) is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma.Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation; increases heart rate and myocardial contractility by stimulating cardiac beta-1 receptors, which increases cardiac output.

【用戶】Bryan

【年級】國三上

【評論內容】ElderlyLower doses may be required?

【用戶】Bryan

【年級】國三上

【評論內容】Isoprenaline (INN) or isoproterenol (USAN, trade names Medihaler-Iso and Isuprel) is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma.Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation; increases heart rate and myocardial contractility by stimulating cardiac beta-1 receptors, which increases cardiac output.

【用戶】Bryan

【年級】國三上

【評論內容】ElderlyLower doses may be required?

【用戶】Tiraxcept

【年級】大一上

【評論內容】(A)Isoproterenol :β1、β2 直接 agonist,α、β的agonist與antagonist皆有證據顯示會隨年齡降低療效(B)Levodopa :代謝成dopamine後直接作用於dopamine受體(C)Pentazocine :鴉片類混和型致效劑μ-antagonist、κ-agonist(D)Metoclopramide :5-HT4 agonist,D2-antagonist,促進腸胃蠕動,治療胃輕癱、消化不良、止吐,有EPS副作用β腎上腺受體療效降低相關文獻:Vestal, Robert E., Alastair JJ Wood, and David G. Shand. "Reduced β‐adrenoceptor sensitivity in the elderly." Clinical Pharmacology & Therapeutics 26.2 (1979): 181-186.

【用戶】Bryan

【年級】國三上

【評論內容】Isoprenaline (INN) or isoproterenol (USAN, trade names Medihaler-Iso and Isuprel) is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma.Produces bronchodilation by relaxing bronchial smooth muscle through beta-2 receptor stimulation; increases heart rate and myocardial contractility by stimulating cardiac beta-1 receptors, which increases cardiac output.

【用戶】Bryan

【年級】國三上

【評論內容】ElderlyLower doses may be required?

【用戶】Tiraxcept

【年級】大一上

【評論內容】(A)Isoproterenol :β1、β2 直接 agonist,α、β的agonist與antagonist皆有證據顯示會隨年齡降低療效(B)Levodopa :代謝成dopamine後直接作用於dopamine受體(C)Pentazocine :鴉片類混和型致效劑μ-antagonist、κ-agonist(D)Metoclopramide :5-HT4 agonist,D2-antagonist,促進腸胃蠕動,治療胃輕癱、消化不良、止吐,有EPS副作用β腎上腺受體療效降低相關文獻:Vestal, Robert E., Alastair JJ Wood, and David G. Shand. "Reduced β‐adrenoceptor sensitivity in the elderly." Clinical Pharmacology & Therapeutics 26.2 (1979): 181-186.