【etrnya】評論

Thrombomodulin functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. This raises the speed of protein C activation thousandfold. Thrombomodulin-bound thrombin has procoagulant effect at the same time by inhibiting fibrinolysis by cleaving thrombin-activatable fibrinolysis inhibitor (TAFI,aka carboxypeptidase B2) into its active form

【大福】評論

https://en.m.wikipedia.org/wiki/File:Coagulation_full.svg

【蔡承叡】評論

thrombomodulin 會跟Protein C 一同作用 抑制凝血反應當缺乏時 凝血反應無法被抑制 造成過度凝血(血栓)