【Klose Liu】評論

Stereotactic body radiation therapy (SBRT) refers to a stereotactic radiotherapy procedure fortreating extracranial tumors with ultrahigh doses per fraction (6 to 30 Gy), in a hypofractionated regimen of five or fewer fractions. SBRT has been mostly applied to the tumors in the spine,lung, liver, pancreas, kidney, and prostate. Because the treatment involves large doses per fraction delivered in a few fractions, conformation of high dose to the target volume together with a rapid fall-off of dose outside the target volume is of critical importance in minimizing damageto normal tissue.  SBRT planning is similar to SRS in that large dose gradients exist within the PTV. Theselarger dose gradients within the PTV also allow for a more rapid dose fall off outside the PTV, sparing more normal tissues.