【終於.......】評論

(1)Mice that were exposed to antibiotics and then challenged with C. difficile developed diarrhea and lost weight. Typical histologic features of CDAD were evident. Oral vancomycin prevented CDAD in all mice, but 68% died from colitis after treatment was discontinued. 參考：A mouse model of Clostridium difficile-associated disease(2)Large bowel disease detected clinically by rectal prolapse was studied in 64 immunodeficient mice (37 athymic NCr-nu/nu, 12 BALB/c AnNCr-nu/nu, 9 C57BL/6NCr-nu/nu, and 6 C.B17/Icr-scid/NCr) naturally infected with Helicobacter hepaticus. Rectal prolapse was found in approximately 5% of immunodeficient mice maintained in a research facility over a period of 3.5 years. All mice had various degrees of chronic proliferative typhlitis, colitis, and proctitis, usually without concomitant hepatitis.Some mice had severe proliferative proctitis with cystic hyperplasia. This new pathogenic bacterial infection should be considered as another potential cause or co-factor for rectal prolapse and large bowel disease in mice.參考：Inflammatory large bowel disease in immunodeficient mice naturally infected with Helicobacter hepaticus參考：https://www.researchgate.net/figure/Gross-and-microscopic-examples-of-rectal-prolapses-A-Normal-female-28-month-old-B6_fig1_230805588(3)原生動物，造成Mice, rats, hamsters, and other rodent species.下痢參考：https://www.ncbi.nlm.nih.gov/books/NBK235394/(4)Spontaneous cases of rectal prolapse in a breeding colony of FVB mice were found to be due to infection with Syphacia obvelata and Citrobacter freundii. 參考：Case report and short communication: Rectal prolapse associated with an unusual combination of pinworms and citrobacter species infection in FVB mice colony