【吳培楷】評論

(A) Fluconazole：阻斷Ergosterol的合成，抑制黴菌細胞膜(B) Caspofungin：抑制β(1-3)glucan，影響黴菌細胞壁形成。      PS:和Cyclosporine並用有肝毒性(C) Amphotericin B：結合處產生孔洞，改變細胞膜通透性。      PS:不可以和NS並用，IV 治療全身性感染。(D) Terbinafine：抑制 Squalene epoxidase，干擾Ergosterol的合成。      療黴舒

【Bryan】評論

Caspofungin is a lipopeptide antifungal drug .It is a member of a new class of antifungals termed the echinocandins. It works by inhibiting the enzyme -β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall. Caspofungin was the first inhibitor of fungal-β-D-glucan synthesis to be approved by the United States FDA. 靜脈注射給藥 治療全身性黴菌感染