【用戶】Bryan
【年級】國三上
【評論內容】Ticlopidine can cause life-threatening hematological adverse reactions, including neutropenia/agranulocytosis, thrombotic thrombocytopenic purpura (TTP) and aplastic anemia.Ticlopidine hydrochloride, after oral ingestion, interferes with platelet membrane function by inhibiting ADP-induced platelet-fibrinogen binding and subsequent platelet-platelet interactions.
【用戶】Bryan
【年級】國三上
【評論內容】Ticlopidine can cause life-threatening hematological adverse reactions, including neutropenia/agranulocytosis, thrombotic thrombocytopenic purpura (TTP) and aplastic anemia.Ticlopidine hydrochloride, after oral ingestion, interferes with platelet membrane function by inhibiting ADP-induced platelet-fibrinogen binding and subsequent platelet-platelet interactions.
【用戶】Wang wang
【年級】高一上
【評論內容】Clopidogrel的機轉作用在ADP receptor, P2Y12受體上。 因為副作用顆粒白血球減少、再生不良性貧血、血小板減少的關係已經較少用的Ticlopidine，也是prodrug，須經代謝(CYP3A4)才能作用，作用於ADP receptor。