問題詳情

1 下列有關化學治療藥品 5-fluorouracil 之敘述,何者正確?
(A) 在人體的半衰期長達 7 天
(B) 連續輸注(continuous-infusion)較 bolus 注射易產生骨髓抑制之副作用
(C) Capecitabine 為 5-fluorouracil 之 prodrug
(D) 腎功能不良之病人使用時劑量須減低

參考答案

答案:C
難度:適中0.588235
統計:A(0),B(1),C(20),D(4),E(0)

用户評論

PHOENIX CHING】評論

半衰期8~20分鐘 Blous容易失效 CI為主

Bonnie】評論

Dosing: Renal Impairment: AdultThere are no dosage adjustments provided in the manufacturer's labeling; use with caution. The following adjustments have been suggested:CrCl <50 mL/minute and continuous renal replacement therapy (CRRT): No dosage adjustment necessary (Aronoff 2007).Hemodialysis:Administer standard dose following hemodialysis on dialysis days (Janus 2010).Administer 50% of standard dose following hemodialysis (Aronoff 2007).Half-life elimination: Following bolus infusion: 8 to 20 minute...

lesbhappy2】評論

IV Bolus: 骨髓抑制IV infusion: 手足症候群

可不可】評論

(D)肝代謝,Bilirubin >5 mg/dL 避免使用。