11.Mice are important toois in basic research and drug development. Conceming transgenic mice and knockoutmice (using CRISPR-Cas9) which statemen ments is/are CORRECT?
(A) The method for injection of the construct into mouse embryos to generate these two mice are similar
(B) The time required for generation of these two mice are similar
(C) Transgenic mice are expressing exogen
(D) The exogenous proteins expressed in transgenic mice are always higher than endogenous proteinsnous gene of interest in vivo
(E) CRISPR-Cas9-mediated deletion but not insertion is the principle for the generation of knockout mice