【Yang Yeh】評論
題幹 摘錄自Caranza Ch5 p69Papillon-Lefevre syndrome (PLS) is one example of a condition that causes severe periodontitis as one of its manifestations. PLS is an autosomal-recessive disorder caused by mutations in the cathepsin C gene located on chromosome 11q14.7 The clinical manifestations of the syndrome include severe aggressive periodontitis and diffuse keratoderma on the palms,the soles,the knees,or all three