問題詳情

76.下列何種抗癌藥會抑制細胞有絲分裂?
(A)Chlorambucil
(B)Cyclophosphamide
(C)Melphalan
(D)Estramustine

參考答案

答案:D
難度:適中0.449882
統計:A(390),B(222),C(321),D(763),E(0)

用户評論

Swear】評論

Estramustine(為estrogen之衍生物)會代謝為estromustine,可接上microtubule-associated protein,以穩定microtubules導致細胞無法分裂而達到毒殺癌細胞作用。Estromustine會再代謝為estrogen及estradiol,故可抑制雄性激素,治攝護腺癌。

Ian】評論

Although this compound was initially designed as an alkylating agent, it has no alkylating activity. • Inhibits microtubule structure and function and the process of microtubule assembly by binding to microtubule-associated proteins (MAPs).

jane90191】評論

只有D跟ABC不同結構分類ABC是nitrogen mustardD是nitrosourea

lolo】評論

樓上~根據micromedexestramustine也是nitrogen mustard耶<