【Swear】評論
Estramustine(為estrogen之衍生物)會代謝為estromustine,可接上microtubule-associated protein,以穩定microtubules導致細胞無法分裂而達到毒殺癌細胞作用。Estromustine會再代謝為estrogen及estradiol,故可抑制雄性激素,治攝護腺癌。
【Ian】評論
Although this compound was initially designed as an alkylating agent, it has no alkylating activity. • Inhibits microtubule structure and function and the process of microtubule assembly by binding to microtubule-associated proteins (MAPs).
【jane90191】評論
只有D跟ABC不同結構分類ABC是nitrogen mustardD是nitrosourea
【lolo】評論
樓上~根據micromedexestramustine也是nitrogen mustard耶<