問題詳情
4. Which of the following statements reflects "circumstantial evidence" for the dopamine theory ofschizophrenia?
(A) Antipsychotic drugs (neuroleptics) act as dopamine agonists,increasing the amount of dopamine in the brain.
(B) Antipsychotic drugs (neuroleptics) can produce symptoms similar tothose of Parkinson's disease (a disorder due to insufficient dopamine).
(C) The drug L-dopa, a dopamine agonist, is used to treat schizophrenicsymptoms in patients with Parkinson's disease.
(D) Amphetamines, which activate dopamine, can lessen psychoticsymptoms in people with schizophrenia.
參考答案
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【樹懶不二家】評論
ANS:(B)抗精神病藥物可以治療Schizophrenia,但會造成類帕金森氏症(Parkinson's disease)的症狀(帕金森氏症的病理是因缺乏Dopamine)(A)抗精神病藥物是Dopamine的拮抗劑(antagonist),會阻斷D2受器(C)L-dopa是合成多巴胺的前驅物質,會通過血腦屏障進入腦部後,合成為dopamine。是治療Parkinson's disease的藥物,但無法治療schizophrenic symptoms.(D)安非他命(amphetamine)會促進Dopamine作用,造成精神症狀,而抗精神病藥物為解毒劑