【用戶】如果詳解被鎖找 北醫王瑞賢
【年級】高一上
【評論內容】【解題】節錄自14th Basic & clinical pharmacology p.1095內文A.omeprazole →為pro-drug，酸性下活化(S=O→S-OH)，與H+/K+ ATPase Cysteine上S形成雙硫鍵→不可逆抑制H+/K+ ATPaseB.antacids →直接中和胃酸→胃PH↑→胃蛋白酶活性↓C.cimetidine →阻H2受體→cAMP↓→抑制胃酸分泌D.sucralfate →酸性活化，與潰瘍組織電性相反，覆蓋形成保護膜【原文】節錄自14th Basic & clinical pharmacology p.1095 It is believed that the negatively charged sucrose sulfate binds to positively charged proteins in the base of ulcers or erosion, forming a physical barrier that restricts furthe...