問題詳情

23.Fibrates可經由活化PPAR-α途徑增加三酸甘油酯等的脂質分解,常用來治療高三酸甘油酯血症(hypertriglyceridemia),其副作用不包括下列何者?
(A)myopathy
(B)arrhythmias
(C)hypoprothrombinemia
(D)high blood levels of aminotransferases or alkaline phosphatase

參考答案

答案:C
難度:困難0.363636
統計:A(1),B(6),C(4),D(0),E(0)

用户評論

【用戶】如果詳解被鎖找 北醫王瑞賢

【年級】高一上

【評論內容】【解題】整理自14th Basic & clinical pharmacology p.635內文1.皮疹(rash)、腸胃道不適、肌肉病變(Myopathy)、心律不整(arrhythmais)2.高aminotransferases、alkaline phosphatase.3.橫紋肌溶解(Rhabdomyolysis)(1)併statin時最常發生(2)若須併statin,fenofibrate為首選4.Fibrate類避免用於肝、腎功能差的病患5.膽結石(cholesterol gallstones)【附上原文】Toxicity Rare adverse effects of fibrates include rashes, gastrointestinal symptoms, myopathy, arrhythmias, hypokalemia, and high blood levels of aminotransferases or alkaline phosphatase. A few patients show decreases in white blood count or hematocrit. Both age...

【用戶】Yuan

【年級】高二下

【評論內容】from . (lange) basic and clinical pharmacology  14e

【用戶】Yuan

【年級】高二下

【評論內容】from . (lange) basic and clinical pharmacology  14e