【用戶】chiehting0719
【年級】小三下
【評論內容】(A)Clevidipine→CCB(B)Darusentan→endothelin receptor antagonist(C)Nebivolol→β1 blocker(D)Aliskiren→renin inhibitors
【用戶】Bryan
【年級】國三上
【評論內容】an 國三上 (2014/06/22 23:38):0人Darusentan is an endothelin receptor antagonist is developing darusentan for the potential treatment of uncontrolled hypertension. 能顯著降低血壓,用於治療肺動脈高血壓內皮素受體拮抗劑: Darusentan ,sitaxentan ,ambrisentan ,bosentan Drug Classes → Cardiovascular Agents → Agents For Pulmonary Hypertension
【用戶】Chelsea Chen
【年級】高二下
【評論內容】臨床試驗顯示ET antagonist 對HFrEF 沒效，darusentan 就是其中一個失敗的案例The effect of selective ET-A receptor blockade was evaluated in the EARTH trial, in which 642 patients with HF (79 percent NYHA class III) and an ejection fraction less than or equal to 35 percent were randomly assigned to one of five doses of darusentan or placebo. At 24 weeks, the primary end point (magnetic resonance measured left ventricular end systolic volume) did not change significantly with any dose of darusentan compared to placebo. There were also no significant changes in symptoms, neurohormone concentrations,...
【用戶】Chelsea Chen
【年級】高二下
【評論內容】臨床試驗顯示ET antagonist 對HFrEF 沒效，darusentan 就是其中一個失敗的案例The effect of selective ET-A receptor blockade was evaluated in the EARTH trial, in which 642 patients with HF (79 percent NYHA class III) and an ejection fraction less than or equal to 35 percent were randomly assigned to one of five doses of darusentan or placebo. At 24 weeks, the primary end point (magnetic resonance measured left ventricular end systolic volume) did not change significantly with any dose of darusentan compared to placebo. There were also no significant changes in symptoms, neurohormone concentrations,...
【用戶】Mushroom
【年級】大三下
【評論內容】selective endothelin receptor antagonist：-sentan(Darusentan ,sitaxentan ,ambrisentan ,bosentan)
【用戶】Mushroom
【年級】大三下
【評論內容】selective endothelin receptor antagonist：-sentan(Darusentan ,sitaxentan ,ambrisentan ,bosentan)