問題詳情

36 王小姐今年 29 歲，規律服用 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 及 paroxetine。因偏頭痛就醫，醫師診察後處方 sumatriptan 治療，下列敘述何者正確？
(A) Sumatriptan 與 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 併用可能增加癲癇發作的風險
(B) Sumatriptan 與 ethinylestradiol 30 mcg/levonorgestrel 125 mcg 併用可能增加中風發作的風險
(C) Sumatriptan 與 paroxetine 併用可能增加 serotonin syndrome 的風險
(D) Sumatriptan 與 paroxetine 併用可能增加癲癇發作的風險

參考答案

答案：C
難度：簡單0.853577
統計：A(18),B(38),C(513),D(32),E(0)

用户評論

【Bryan】評論

Paroxetine (also known by the trade name Paxil among others) is an antidepressant drug of the SSRI type.Sumatriptan :Serotonin 興奮劑

【Bryan】評論

Sumatriptan binds with high affinity to human cloned 5-HT1B/1D receptors. IMITREX presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT1B/1Dreceptors located on intracranial blood vessels and sensory nerves of the trigeminal system.

【Rose Tsai】評論

Sumatriptan和避孕藥無交互作用

【Bryan】評論

Sumatriptan binds with high affinity to human cloned 5-HT1B/1D receptors. IMITREX presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT1B/1Dreceptors located on intracranial blood vessels and sensory nerves of the trigeminal system.

【OOO】評論

Sumatriptan 是 5-HT1B/1D receptors 的致效劑，主要治療偏頭痛。Paroxetine是SSRI，阻斷血清素再吸收，增加血清素在血液中的濃度，治療憂鬱症。