【用戶】Bryan
【年級】國三上
【評論內容】Carbapenems are a class of beta-lactam antibiotics. They have broad-spectrum antibacterial activity, being active against many aerobic and anaerobic gram-positive and gram-negative organisms.Carbapenems inhibit bacterial cell wall synthesis by binding to the penicillin binding proteins and interfering with cell wall formation. They are extremely resistant to beta-lactamase enzymes, making them very useful in treating bacterial infections where beta-lactamase is produced that makes other beta-lactam antibiotics ineffective...
【用戶】Camille Hsu
【年級】高一下
【評論內容】Carbapenems是β-lactam抗生素中的一類,它與傳統β-lactam抗生素的不同主要在於化學結構式中的β-lactam環內第2及第3位置間比Penicillin多了一個不飽和鍵,且β-lactam環中的硫原子也被碳原子所取代,也因而讓此類抗生素不易被β-lactamase所破壞,臨床上常用的此類抗生素包括了Imipenem/Cilastatin、Meropenem 和Ertapenem,但Ertapenem對綠膿桿菌(Pseudomonas aeruginosa)先天就無效ref:Meropenem 與 Imipenem/Cilastatin 的臨床治療與使用時機 中興醫院 一般內科 蔡正堅 醫師
【用戶】Bryan
【年級】國三上
【評論內容】Carbapenems are a class of beta-lactam antibiotics. They have broad-spectrum antibacterial activity, being active against many aerobic and anaerobic gram-positive and gram-negative organisms.Carbapenems inhibit bacterial cell wall synthesis by binding to the penicillin binding proteins and interfering with cell wall formation. They are extremely resistant to beta-lactamase enzymes, making them very useful in treating bacterial infections where beta-lactamase is produced that makes other beta-lactam antibiotics ineffective...
【用戶】Camille Hsu
【年級】高二下
【評論內容】Carbapenems是β-lactam抗生素中的一類,它與傳統β-lactam抗生素的不同主要在於化學結構式中的β-lactam環內第2及第3位置間比Penicillin多了一個不飽和鍵,且β-lactam環中的硫原子也被碳原子所取代,也因而讓此類抗生素不易被β-lactamase所破壞,臨床上常用的此類抗生素包括了Imipenem/Cilastatin、Meropenem 和Ertapenem,但Ertapenem對綠膿桿菌(Pseudomonas aeruginosa)先天就無效ref:Meropenem 與 Imipenem/Cilastatin 的臨床治療與使用時機 中興醫院 一般內科 蔡正堅 醫師