問題詳情

50 醫師欲使用isoniazid、rifampin、ethambutol、pyrazinamide 來治療 65 歲、身高155 公分、體重48 公斤之女性肺結核病患 (tuberculosis) 。她的血中肌胺酸酐 (serum creatinine) 值為 4.0 mg/dL ，ALT (alanine aminotransferase)、AST (aspartate aminotransferase) 分別為10 與15 U/L，請問上述四種藥品那些需要調整劑量？
(A)病人肝、腎功能都正常，四種藥都不需調整劑量
(B)病人腎功能不佳，四種藥都要調整劑量
(C)病人腎功能不佳，ethambutol、pyrazinamide 要調整劑量
(D)病人肝功能不佳，isoniazid、rifampin 要調整劑量

參考答案

答案：C
難度：適中0.618421
統計：A(4),B(5),C(47),D(5),E(0)

用户評論

【Bryan】評論

Isoniazin、rifampin 肝毒性，ethambutol,pyriainamide 腎毒性

【我愛阿，阿愛我】評論

Normal levels of creatinine in the blood are approximately 0.6 to 1.2 mg/dL in adult males and 0.5 to 1.1 mg/dL in adult females.Creatinine levels that reach 2.0 or more in babies and 10.0 or more in adults may indicate severe kidney impairment Alanine aminotransferase1Males:10–40 units per liter (U/L) or 0.17–0.68 microkats per liter (mckat/L)Females:7–35 U/L or 0.12–0.60 mckat/LAspartate aminotransferase (AST)1Males:14–20 units per liter (U/L) or 0.23–0.33 microkats per liter (mckat/L)Females:10–36 U/L or 0.17–0.60 mckat/...

【我愛阿摩，阿摩愛我】評論

Normal levels of creatinine in the blood are approximately 0.6 to 1.2 mg/dL in adult males and 0.5 to 1.1 mg/dL in adult females.Creatinine levels that reach 2.0 or more in babies and 10.0 or more in adults may indicate severe kidney impairment Alanine aminotransferase1Males:10–40 units per liter (U/L) or 0.17–0.68 microkats per liter (mckat/L)Females:7–35 U/L or 0.12–0.60 mckat/LAspartate aminotransferase (AST)1Males:14–20 units per liter (U/L) or 0.23–0.33 microkats per liter (mckat/L)Females:10–36 U/L or 0.17–0.60 mckat/...