27.Which of the following description about autonomic, endocrine and immune interactions in painis correct?
(A)Signaling from the immune system to the CNS via vagal afferents and possibly small-diameterafferents innervating somatic tissues to induce sickness behavior
(B) Modulation of the immune system and the inflammatory response by CNS circuits that controlthe production and release of neuroendocrine hormonal mediators in the sympathoadrenal stressaxis
(C)Coupling of the sensory nociceptive and sympathetic efferent components of the peripheralnervous system in the setting of inflammation and nerve injury to produce sympatheticallymaintained pain
(D) All of above