問題詳情

71.若病人服藥adherence良好,下列何者最可能有「藥品劑量不足」的問題?
(A)55歲hypertension病人(無其他疾病),服用amlodipine 5 mg QD一個月後,測得血壓135/80 mmHg
(B)60歲type 2 DM病人,服用metformin 500 mg QD三個月後,測得Hb

7.8%
(C)65歲atrial fibrillation病人,服用warfarin 5 mg QD二星期後,測得INR 3.2
(D)70歲grand mal seizure病人服用phenytoin 300 mg QD 一個月後,測得phenytoin血中濃度22 mg/L

參考答案

答案:B
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用户評論

wucacasi】評論

(A) <60歲要控制在<140/90 (☆)...

socket】評論

(C) AF患者的INR控制在2-3,此患者INR 3.2 ->劑量稍高Vitamin K antagonist — For patients with AF treated with VKA (eg, warfarin), an INR between 2.0 and 3.0 is recommended with an average annual TTR >70 percent [21,22]. This is based upon the increased risk of stroke observed with INR values significantly below 2 (four- to sixfold at an INR of 1.3 compared with an INR of 2 or above) and the increased risk of bleeding associated with INR above 3.0 .Advanced age (over 74 years) is an independent risk factor for bleeding during anticoagulation as well as a risk factor for stroke. However, ...

強力施巴】評論

B選項小細節來自考古題Metformin 劑量應為500mg BID