【用戶】Lan
【年級】高三上
【評論內容】3.下列何種藥物會與其作用之標的（target）產生共價結合？ (A)Phenoxybenzamine (B)Phenylephrine (C)Physostigmine (D)Pilocarpine 專技 - 藥理學與藥物化學- 107 年 - 107-1-藥師(一)藥理學與藥物化學#67577答案：A 28.一位病人的腎上腺腫瘤被診斷為嗜鉻母細胞瘤（pheochromocytoma）且不能以開刀去除，下列何者是最適 用的治療藥物？ (A)Phenylephrine (B)Phenoxybenzamine (C)Norepinephrine (D)Epinephrine 專技 - 藥理學與藥物化學- 107 年 - 第一次專技高考/藥理學與藥物化學#67577答案：B56.下列何者為phenoxybenzamine與α-adrenoceptors間主要之作用力？ (A)離子鍵 (B)共價鍵 (C)氫鍵 (D)凡得瓦爾力 專技 - 藥理學與...
【用戶】我愛阿，阿愛我
【年級】
【評論內容】Phenoxybenzamine is used as an anti-hypertensive due to its efficacy in reducing the vasoconstriction caused by epinephrine (adrenaline) and norepinephrine. Phenoxybenzamine forms a permanent covalent bond with adrenergic receptors. Based on known information about the structures of these receptors, it likely involves attack by the cysteine at position 3.36 in transmembrane helix 3 to form a stable linkage.[6] Thus, it remains permanently bound to the receptor, preventing adrenaline and noradrenaline from binding. This causes vasodilatation in blood vessels, due to its antagonistic effect at t...
【用戶】所得皆所愿
【年級】大三上
【評論內容】補充共價鍵結：種類α-antagonist抗腫瘤抗憂鬱Loop不可逆AcHEI藥物Phenoxybenzamine烷化劑：Mechlorethamine抗代謝：5-FUMAOI -B：SelegilineEthacrynic acid有機磷殺蟲劑：Parathion