問題詳情

10.Paroxysmal nocturnal hemoglobinuria是因為下列何種基因突變所造成?
(A)glycophorin A
(B)phosphatidylinositol glycan protein A
(C)α spectrin
(D)ankyrin

參考答案

答案:B
難度:簡單0.716172
統計:A(55),B(217),C(15),D(16),E(0)

用户評論

etrnya】評論

Paroxysmal nocturnal haemoglobinuria (PNH), an acquired clonal blood disorder, is caused by the absence of glycosyl phosphatidylinositol (GPI)-anchored surface proteins due to a defect in a specific step of GPI-anchor synthesis. The cDNA of the X-linked gene, PIG-A, which encodes a protein required for this step has recently been isolated.

橘子捲】評論

早期用Ham's test,目前用流式細胞儀。