【Swear】評論
Didanosine is an antiretroviral medication used to treat AIDS as part of highly active antiretroviral therapy (HAART). It is of the reverse transcriptase inhibitor class.
【吳培楷】評論
治療AIDS的 NRTI 藥物:Zido☆☆☆☆☆☆ ...
【所得皆所愿】評論
Didanosine(ddI):NRTIs> 機轉:於宿主細胞內轉化為ddATP,繼而插入DNA鏈中,造成DNA鏈的增長中止> 耐酸;可以口嚼錠、緩衝錠、緩衝溶液投與> 代謝後產生尿酸(通風患者注意)> 副作用:胰臟炎、周邊神經毒性(劑量限制)> 核酸衍生物:Inosine