用戶【不要叫我黃藥師】點評問題和點評內容

【評論主題】32.下列何者為治療NSAIDs引發消化性潰瘍的首選?(A)dinoprostone (B)famotidine (C)lansoprazole (D)misoprostol

【評論內容】If the NSAID was discontinued and A.D.’s treatment was continued with alternative therapy such as oxycodone, a PPI is the preferred treatment to heal theulcer because it provides a more rapid rate of ulcer healing (4 weeks) and symptom relief than an H2RA or sucralfate (6–8 weeks).Because the naproxen was reinstituted at discharge in the presence of an active ulcer, a PPI is the drug of choice, because potent acid suppression is required to heal the ulcer and relieve the symptoms. The duration of PPI therapy should be extended from 4 weeks to 8 to 12 weeks as continuing the offending NSAID will interfere with ulcer healing.PPI為治療NSAID引起的消化性潰瘍首選(因為其效果和緩解症狀的時間較快)Ref Applied

【評論主題】2.一般而言,下列何種肺炎要考慮使用經驗性抗生素來治療黴漿菌(Mycoplasma pneumoniae)?(A)社區肺炎(community-acquired pneumonia) (B)醫療照護相

【評論內容】

大家記得社區型肺炎的定義嗎><

社區型肺炎:在社區內發生之肺炎,稱為社區型肺炎(住院48小時前發生的是社區型肺炎)

社區型肺炎典型致病菌:Streptococcus pneumoniae,Haemophilus influenza

社區型肺炎非典型致病菌:前人口訣CML

Chlamydophila pneumoniae,Mycoplasma pneumoniae, Legionella species

         披衣菌                                黴漿菌                           退伍軍人菌

再來就是經驗性抗生素的部分

一般無共病者 :Macrolide或Doxycycline

有共病者: β-lactam+Macrolide

有共病者且過去三個月曾使用抗生素,DRSP risk factor,居住地有高盛行率的DRSP:

β-lactam+Macrolide或Respiratory FQ(Moxi,Levo,Gemi)

DRSP risk factor包含<2歲或>65歲(小孩及老人)

                                    過去三個月曾使用β-lactam抗生素

                                    酒精濫用者

                                    有疾病共病者

                                    自體免疫疾病或採免疫抑制療法(器官移植者)

                                    小孩日間照顧中心工作者Ref.Applied

【評論主題】78 Malathion 在 carboxyesterase 之作用下變成:(A)Malathion acid(B)Malaoxon(C)Parathion(D)Paraoxon

【評論內容】https://www.research☆☆☆☆.☆☆☆/...

【評論主題】17.有關淋巴瘤(lymphoma)之敘述,下列何者正確?(A)淋巴瘤可分為Hodgkin lymphoma與non-Hodgkin lymphoma,其中以前者占大宗 (B)少數淋巴瘤的發生與病毒感

【評論內容】Radiologic evaluation includes computerized tomography or PET to evaluate the extent of disease.

【評論主題】61 下列何種藥物可預防或減輕因使用 Aspirin 造成之消化性潰瘍?(A) Biscodyl (B) Lactulose (C) Misoprostol (D) Sorbitol

【評論內容】

Musoprostol是前列腺素E1的類似物,具有保護胃黏膜的效果

【評論主題】50 Cabamazepine 主要作用於下列何種離子通道(ion channel) ,而用於 partial seizure 之治療?(A)鈣 (B)氯 (C)鉀 (D)鈉

【評論內容】

Phenytoun,Carbamazepine都是影響鈉離子通道,可用於治療局部性發作或全身性發作