【terminator812】評論

NSAID-induced ulcer — Patients with NSAID-associated ulcers should be treated with a PPI (eg, omeprazole 20 to 40 mg daily) for four to eight to weeks based on the size of the ulcer (table 1). In patients with peptic ulcers who need to remain on NSAIDs or aspirin, maintenance antisecretory therapy with a PPI (eg, omeprazole 20 mg daily) can reduce the risk of ulcer complications or recurrence [14]. (See "NSAIDs (including aspirin): Secondary prevention of gastroduodenal toxicity", section on 'Secondary prevention of gastroduodenal toxicity' and 'Prevention of recurrence' below.)Peptic ulcer disease: Treatment and secondary prevention - UpToDate

【不要叫我黃藥師】評論

If the NSAID was discontinued and A.D.’s treatment was continued with alternative therapy such as oxycodone, a PPI is the preferred treatment to heal theulcer because it provides a more rapid rate of ulcer healing (4 weeks) and symptom relief than an H2RA or sucralfate (6–8 weeks).Because the naproxen was reinstituted at discharge in the presence of an active ulcer, a PPI is the drug of choice, because potent acid suppression is required to heal the ulcer and relieve the symptoms. The duration of PPI therapy should be extended from 4 weeks to 8 to 12 weeks as continuing the offending NSAID will interfere with ulcer healing.PPI為治療NSAID引起的消化性潰瘍首選(因為其效果和緩解症狀的時間較快)Ref Applied

【m60406】評論

70.林老太太因退化性關節炎長期使用acetaminophen及酸痛貼布，曾多次胃出血；最近膝蓋疼痛加劇。