問題詳情

95 一位 73 歲男性數度發生呼吸困難，並出現心包囊及肋膜腔積水，影像學檢查發現肝腫大充血，尿中5-hydroxyindoleacetic acid 為 40 mg/24 小時（正常值為 0.7-8.2 mg/24 小時）。病人後來接受肺動脈瓣及三尖瓣置換手術，下列敘述中何者最符合此病人右心瓣膜的病理變化？
(A) Deposition of mucoid material in spongiosa
(B) Calcification and fibrosis at the base of valves
(C) Plaque-like intimal thickening and smooth muscle cell proliferation
(D) Subendocardial accumulation of elastic fibers

參考答案

答案：C
難度：非常困難0.125
統計：A(0),B(1),C(5),D(0),E(0)

用户評論

【用戶】Chris

【年級】高三下

【評論內容】5-Hydroxyindoleacetic acid (5-HIAA) is the main metabolite of serotonin.Carcinoid tumors elaborate bioactive products (e.g.,serotonin, kallikrein, bradykinins, histamine, prostaglandins,and tachykinins P and K) that can cause cardiac lesions. The precise agent responsible is uncertain, although it is presumably rapidly etabolized in lung and liver, because cardiac lesions do not occur unless there is extensive hepatic metastatic spread. Right-sided heart lesions (valvular and endocardial) predominate.• Lesions are characterized by plaque-like intimal thickening (composed of smooth muscle cell...