問題詳情

11.有關Clopidogrel之抗凝血作用，下列敘述何者錯誤？
(A)不可逆抑制血小板之ADP receptor
(B)屬於thienopyridine衍生物
(C)會影響前列腺素代謝
(D)比ticlopidine的副作用少

參考答案

答案：C
難度：適中0.54506
統計：A(328),B(308),C(1506),D(621),E(0)

用户評論

【安】評論

(C)Aspirin不可逆抑制COX，會影響前列腺素代謝(D)Ticlopidine副作用：顆粒性白血球缺乏症(Agranulocytosis)[使用需監測ANC]

【claire】評論

Clopidogrel (top left) being activated: The first step is an oxidation mediated (mainly) by CYP2C19, unlike the activation of the related drug prasugrel. The two structures at the bottom are tautomers of each other; and the final step is a hydrolysis.