問題詳情

65 Azathioprine 與 allopurinol 的藥品交互作用之成因係共用下列何種酵素?
(A) Hypoxantine-guanine phosphoribosyltransferase(HGPRT)
(B) Xanthine oxidase
(C) Phophoribosyl-1 pyrophosphate(PRPP)synthetase
(D) Cytochrome P 450 3A4

參考答案

答案:B
難度:非常簡單0.903808
統計:A(7),B(451),C(5),D(7),E(0)

用户評論

【用戶】粗暴言論duck不必

【年級】大一上

【評論內容】The concomitant administration of allopurinol and azathioprine or mercaptopurine requires a dose reduction to one-third to one-fourth of the usual dose of the thiopurine because concomitant administration could increase plasma concentrations of these thiopurines, resulting in severe toxicity.reference: uptodate