問題詳情

25 Mantle cell lymphoma 最常出現的染色體異常為何？
(A) t(11; 14)
(B) t(9; 22)
(C) t(15; 17)
(D) trisomy 12

參考答案

答案：A
難度：簡單0.86
統計：A(129),B(12),C(8),D(1),E(0)

用户評論

【PPMTPASS】評論

MCL is a subtype of B-cell lymphoma, due to CD5 positive antigen-naive pregerminal center B-cell within the mantle zone that surrounds normal germinal center follicles. MCL cells generally over-express cyclin D1 due to a t(11:14)chromosomal translocation in the DNA. More specifically, the translocation is at t(11;14)(q13;q32).