【用戶】Celeste
【年級】小四上
【評論內容】(D)口服給藥後,活性大於 estradiol:Hepatic. Quantitatively, the major metabolic pathway for ethinyl estradiol, both in rats and in humans, is aromatic hydroxylation, as it is for the natural estrogens.2β-OH-17β-ethinylestradiol
【用戶】Celeste
【年級】小四上
【評論內容】item1515.15.下列何者口服無效? (A)Methestrol (B)Dienestral (C)Estradiol (D)Diethylstibestrol專技高考◆藥師(一)◆藥理學與藥物化學- 2015年 - 104-2-藥師(一)-藥理學與藥物化學#23933
【用戶】Celeste
【年級】小五上
【評論內容】(D)口服給藥後,活性大於 estradiol:Hepatic. Quantitatively, the major metabolic pathway for ethinyl estradiol, both in rats and in humans, is aromatic hydroxylation, as it is for the natural estrogens.2β-OH-17β-ethinylestradiol
【用戶】Quinine
【年級】高二上
【評論內容】(B)在foye's 7 th P.1393有提到,mestranol是prodrug,為3-O-methyl ether of ethinyl estradiol(EE)(就是3號位接methoxy的意思~),口服後經肝O-demethylation,就會變成EE~