【用戶】Holmes

【年級】國一上

【評論內容】RNA Sequencing (RNA-Seq) is much better, because it allows us to define the fusion gene directly, as well as the consequence of the chromosomal translocation. Targeting genes that are more relevant in this process enables us to identify the partners in the translocation, which is a major advantage. With RNA-Seq, we can also measure gene expression in the amount of RNA.Fusion genes are the consequence of chromosomal translocation or internal deletions.Translocations are the most common molecular rearrangement events that we see in leukemia.因為fusion gene 最常發生在轉譯的時候，所以偵測RNA為佳。參考資料: https://www.illumina.com/science/customer-stories/icommunity-customer-interviews-case-studies/cazzaniga-milan-interview-targeted-gene-panel.html

【用戶】辛辛

【年級】高三下

【評論內容】CML基因檢測—定性檢測【RNA 檢體；RT-PCR】CML基因檢測—定量檢測【RNA 檢體；Q-PCR】AML基因檢測—定性檢測【RNA 檢體；RT-PCR】骨髓增生性疾病基因檢測【BCR-ABL1 為 RNA 檢體，其餘為 DNA 檢體】 參考：

【用戶】Holmes

【年級】國一上

【評論內容】RNA Sequencing (RNA-Seq) is much better, because it allows us to define the fusion gene directly, as well as the consequence of the chromosomal translocation. Targeting genes that are more relevant in this process enables us to identify the partners in the translocation, which is a major advantage. With RNA-Seq, we can also measure gene expression in the amount of RNA.Fusion genes are the consequence of chromosomal translocation or internal deletions.Translocations are the most common molecular rearrangement events that we see in leukemia.因為fusion gene 最常發生在轉譯的時候，所以偵測RNA為佳。參考資料: https://www.illumina.com/science/customer-stories/icommunity-customer-interviews-case-studies/cazzaniga-milan-interview-targeted-gene-panel.html

【用戶】辛辛

【年級】高三下

【評論內容】CML基因檢測—定性檢測【RNA 檢體；RT-PCR】CML基因檢測—定量檢測【RNA 檢體；Q-PCR】AML基因檢測—定性檢測【RNA 檢體；RT-PCR】骨髓增生性疾病基因檢測【BCR-ABL1 為 RNA 檢體，其餘為 DNA 檢體】 參考：