問題詳情

50.有關排卵藥clomiphene citrate敘述,下列何者錯誤?
(A)主要可以治療促性腺激素低下型低性腺功能症(hypogonadotropic hypogonadism WHO group I)患者的無排卵現象
(B)選擇性雌激素接受器調節劑,可以影響雌激素負回饋反應,刺激濾泡發育
(C)治療的副作用可能包括子宮頸黏液分泌減少、子宮內膜生長受損以及多胞胎妊娠
(D)某些病患治療後仍然無法排卵時,可以結合胰島素增敏劑metformin,增加排卵的機會

參考答案

答案:A
難度:困難0.375
統計:A(9),B(4),C(4),D(2),E(0)

用户評論

【用戶】霸氣阿宏

【年級】小二上

【評論內容】由於hypogonadotropic hypogonadism 是本身無法分泌FSH與LH,因此抑制雌激素的副回饋仍然無法解決問題。須解決其根本因素,如: brain or pituitary tumors, pituitary apoplexy, head trauma, ingestion of certain drugs, and certain systemic diseases and syndromes.Mechanism of Action  (clomiphene)Clomiphene is a racemic mixture consisting of zuclomiphene (~38%) and enclomiphene (~62%), each with distinct pharmacologic properties. Clomiphene acts at the level of the hypothalamus, occupying cell surface and intracellular estrogen receptors (ERs) for longer durations than estrogen. This interferes with rece...

【用戶】霸氣阿宏

【年級】小二上

【評論內容】由於hypogonadotropic hypogonadism 是本身無法分泌FSH與LH,因此抑制雌激素的副回饋仍然無法解決問題。須解決其根本因素,如: brain or pituitary tumors, pituitary apoplexy, head trauma, ingestion of certain drugs, and certain systemic diseases and syndromes.Mechanism of Action  (clomiphene)Clomiphene is a racemic mixture consisting of zuclomiphene (~38%) and enclomiphene (~62%), each with distinct pharmacologic properties. Clomiphene acts at the level of the hypothalamus, occupying cell surface and intracellular estrogen receptors (ERs) for longer durations than estrogen. This interferes with rece...