【用戶】IG:Pharmabook

【年級】高一上

【評論內容】Koda & kimble 10th applied  CASE 96-6, QUESTION 3 (A)一旦病人在血中驗出CMV病毒，雖沒有臨床症狀，仍要使用抗病毒藥物治療In patients who are CMV-seropositive or who have received a CMV-seropositive graft, antiviral drugs are essential to minimize morbidity associated with CMV reactivation or secondary infection (B)CMV病毒血症的出現與免疫力低下有關，應考慮適當調整免疫抑制劑劑量CMV has the ability to establish lifelong latent infection after primary exposure. In immunocompromised patients, the virus may reactivate, resulting in asymptomatic shedding or the development of CMV disease (C)Ganciclovir 容易造成全血球低下（pancytopenia）However, prophylactic ganciclovir therapy is associated with neutropenia in 30% of patients, which contributes to an increased risk of invasive bacterial and fungal infections (D)Immunoglobulin合併ganciclovir用於CMV引起的肺炎 Data regarding the use of immunoglobulins as adjunctive therapy for the treatment of select infections in the neutropenic cancer patient are primarily limited to case reports. Patients with pneumonia secondary to CMV may benefit from adjunctive immunoglobulin therapy (in combination with ganciclovir). CASE 96-6, QUESTION 3: S.D. is also CMV-seropositive.What is the significance of this finding, and what measures can be taken to prevent reactivation of CMV?

【用戶】IG:Pharmabook

【年級】高一上

【評論內容】Koda & kimble 10th applied  CASE 96-6, QUESTION 3 (A)一旦病人在血中驗出CMV病毒，雖沒有臨床症狀，仍要使用抗病毒藥物治療In patients who are CMV-seropositive or who have received a CMV-seropositive graft, antiviral drugs are essential to minimize morbidity associated with CMV reactivation or secondary infection (B)CMV病毒血症的出現與免疫力低下有關，應考慮適當調整免疫抑制劑劑量CMV has the ability to establish lifelong latent infection after primary exposure. In immunocompromised patients, the virus may reactivate, resulting in asymptomatic shedding or the development of CMV disease (C)Ganciclovir 容易造成全血球低下（pancytopenia）However, prophylactic ganciclovir therapy is associated with neutropenia in 30% of patients, which contributes to an increased risk of invasive bacterial and fungal infections (D)Immunoglobulin合併ganciclovir用於CMV引起的肺炎 Data regarding the use of immunoglobulins as adjunctive therapy for the treatment of select infections in the neutropenic cancer patient are primarily limited to case reports. Patients with pneumonia secondary to CMV may benefit from adjunctive immunoglobulin therapy (in combination with ganciclovir). CASE 96-6, QUESTION 3: S.D. is also CMV-seropositive.What is the significance of this finding, and what measures can be taken to prevent reactivation of CMV?