問題詳情
67.可用於治療肺高壓(pulmonary hypertension)藥物的作用機轉,不包括下列何者?
(A)endothelin antagonist
(B)phosphodiesterase E5 inhibitor
(C)soluble guanylyl cyclase activator
(D)calcitonin gene-related peptide(CGRP)antagonist
參考答案
答案:B,D
難度:非常困難0.142857
統計:A(12),B(14),C(11),D(22),E(3)
用户評論
【Chris】評論
CGRP is the most potent vasodilator yet discovered. It dilates multiple vascular beds, but the coronary circulation is particularly sensitive. The vasodilation is mediated via a nonendothelial mechanism through activation of adenylyl cyclase.