【用戶】我愛阿,阿愛我
【年級】
【評論內容】Oral amiodarone is markedly lipophilic, resulting in a very large volume of distribution (average about 66 L/kg) and a prolonged time to reach stable plasma levels [1]. It is incompletely absorbed (approximately 30 to 70 percent) after oral administration and is taken up very extensively by tissue, with marked interindividual variation [2]. Estimates of the elimination half-life of amiodarone vary, depending on how the half-life has been measured and the route of amiodarone administration. The relatively short half-life for disappearance of amiodarone from plasma after a single-dose or short...
【用戶】我愛阿摩,阿摩愛我
【年級】
【評論內容】Oral amiodarone is markedly lipophilic, resulting in a very large volume of distribution (average about 66 L/kg) and a prolonged time to reach stable plasma levels [1]. It is incompletely absorbed (approximately 30 to 70 percent) after oral administration and is taken up very extensively by tissue, with marked interindividual variation [2]. Estimates of the elimination half-life of amiodarone vary, depending on how the half-life has been measured and the route of amiodarone administration. The relatively short half-life for disappearance of amiodarone from plasma after a single-dose or short...