【justin1999031】評論

  By far the commonest cause is hypoxic–ischaemic encephalopathy. It may be responsible for 80% of all seizures in the first 2 days of life. Brain damage due to prenatal distress and malformations of cortical development is being increasingly recognised.  Seizures in neonates can be difficult to diagnose because they often present with subtle signs and symptoms.     新生兒時期發作臨床表現上與其他時期有相當明顯不同，大部分的發作以局部為主，Subtle seizure(細微發作)為最常發生的類型，而常見於其他時期的全面強直-陣攣發作(Generalized tonic-clonic seizures)幾乎不會在新生兒時期發生。    細微發作(Subtle Seizures): 約佔50%，不一定同時發現腦波的不正常放電。常見於足月兒但也可見於早產兒。眼部動作(Ocular movements)，包含眼球隨意或無意義飄移、雙眼持續性共軛強直的往一邊水平偏移有時可合併眼球抖動(jerking)、不斷眨眼眼瞼顫動、翻白眼、凝視、突然張眼、以及眼球震顫。