1.Enhancer function underlies regulatory processes by which cells establishpatterns of gene expression. Which of the following descriptions about enhancer isnot correct?
(A) Enhancer works as cis-regulatory elements to mediate spatiotemporal control ofgene expression.
(B) Enhancers can be identified using a reporter gene. Once a reporter gene isintegrated near an enhancer, its expression reflects the expression pattern.
(C) Next-generation sequencing (NGS)-based approach called RNase-seq enablesidentification of enhancers.
(D) Enhancer help recruit RNA polymerase II to promoters and can attract variouschromatin-modifying enzymes to DNA.
(E) Enhancer is distal sequences that lie upstream or downstream of the corepromoter and recruit transcription factors