問題詳情

7 Clorazepate 在胃中會進行脫羧(decarboxylation)反應,所得產物與以下何藥物之主要代謝物相同?
(A) Diazepam
(B) Lorazepam
(C) Flurazepam
(D) Loprazolam

參考答案

答案:A
難度:適中0.461538
統計:A(6),B(4),C(1),D(1),E(0)

用户評論

Bryan】評論

Clorazepate (marketed under the brand names Tranxene and Novo-Clopate), also known as clorazepate dipotassium, is a drug that is a benzodiazepine derivativeSince orally administered Clorazepate dipotassium is rapidly decarboxylated to form (nordiazepam), there is essentially no circulating parent drug. Nordiazepam, the primary metabolite, quickly appears in the blood and is eliminated from the plasma with an apparent half-life of about 40 to 50 hours.