問題詳情

67.樹突細胞可以誘導調節性T細胞的分化，下列那個分子與此功能無直接關聯？
(A)IL-10
(B)TGF-β
(C)Indoleamine 2, 3 dioxygenase（IDO）
(D)IL-6

參考答案

答案：D
難度：困難0.35
統計：A(18),B(8),C(11),D(28),E(0)

用户評論

【Chian Yun Ho】評論

IL 6: causes fever and stimulates production of acute-phase protein

【Chris】評論

 Increasing  expression  of  the  anti-inflammatory  enzyme  indoleamine 2,3-dioxygenase (IDO) by treatment with IFN-γ or by unmethylated CpG DNA can induce the generation or activation of Treg  cells. Tumors can produce enzymes that act to suppress local immune responses. The enzyme indoleamine 2,3-dioxygenase (IDO) catabolizes tryptophan, an essential amino acid, in order to produce the immuno suppressive metabolite  kynurenine.  IDO  seems  to  function  in  maintaining  a  balance between  immune  responses  and  tolerance  during  infections,  but  can  be indu...