5. Which of following description about using anticonvulsants (used as Analgesic Drugs is"Correct"?
(A) Most commonly used anticonvulsants as analgesics appear to work through potentiation ofvoltage-gated sodium and calcium channels
(B) Sodium channel subtype 1.4 &1.5 are highly expressed in neuronal cell and could be the drugtarget for anticonvulsant medication
(C) Gabapentinoid (Gabapentin & Pregabalin) works on GABA receptor
(D) Topiramate works only on voltage-gated sodium channel
(E) Lamotrigine and Phenytoin work on voltage-gated sodium channelsAns: E Chap 35&36