【評論主題】1 下列那個藥物常與Methotrexate 合用以減少抗癌藥的毒性？(A)Folic acid(B)Leucoverin(C)Nicotinic acid(D)Nicotinamide
【評論內容】
Methotraxate 抑制folic acid 活化
Leucoverin 為folic acid活化態
【評論主題】61 下列何者與cyclosporine 併用時，會因為抑制其代謝而使腎毒性增加？(A)Verapamil(B)Carbamazepine(C)Chloramphenicol(D)Cimetidine
【評論內容】Cyclosporine: CYP3A4 ...
【評論主題】74 甲醇中毒（Methanol intoxication）時，可以以靜脈注射下列何種藥物來延緩甲醇的毒性代謝產物產生？(A)異丙醇（Isopropanol） (B)乙醇（Ethanol）(C)乙烯乙
【評論內容】
乙醇會與甲醇競爭代謝酵素
【評論主題】49 下列何者不是Adrenocorticosteroids 常見之副作用？(A) Cushing 症候群 (B)低血糖 (C)骨質疏鬆症 (D)傷口癒合變慢
【評論內容】
Cushing’s syndrome arises from the repeated hypersecretion of glucocorticoids.
Some symptoms of an individual with Cushing's syndrome include low tissue protein levels, due to muscle and bone atrophy, and high blood glucose levels.
【評論主題】3 下列何種配醣體屬於S-glycoside？(A) Sinigrin (B) Prunasin (C) Ginsenoside Rg1 (D) Glycyrrhizin
【評論內容】
(A) Sinigrin：S(B) Prunasin、(C) Ginsenoside Rg1、(D) Glycyrrhizin：O
【評論主題】24 矽膠（Silica gel）為薄層層析法常用之固定相，其分析物之 R f 值大小，取決於矽膠上何種官能基與分析物作用之程度？(A)胺基(B)醛基(C)酮基(D)氫氧基
【評論內容】矽膠結構：矽膠為極性固定相，.....看...
【評論主題】28 下列何者可以與毒素（Toxins）結合保護消化道？(A)Pectin(B)Agar(C)Amylose(D)Acacia
【評論內容】Pectin is an adsorbe☆☆ ☆☆☆ ☆☆☆☆...
【評論主題】31 HMG-CoA reductase 與下列那一種化合物之生合成有關係？(A)Steroid(B)Cardiac glycoside(C)Insulin(D)Thyroid hormone
【評論內容】Acetyl-CoA➡️HMG-CoA➡️Meva.....看完整詳解
【評論主題】1 下列那個藥物常與Methotrexate 合用以減少抗癌藥的毒性？(A)Folic acid(B)Leucoverin(C)Nicotinic acid(D)Nicotinamide
【評論內容】
Methotraxate 抑制folic acid 活化
Leucoverin 為folic acid活化態
【評論主題】53 下列何者為Coronary vasodilator 且為第四型抗心律不整藥物？(A)Propranolol(B)Sotalol(C)Verapamil(D)Procainamide
【評論內容】ClassKnown asExamplesMechanismIaFast-channel blockersQuinidineAjmalineProcainamideDisopyramideNa+channel block and K+ channel blocking effectIbLidocainePhenytoinMexiletineTocainideNa+ channel block (fast)IcEncainideFlecainidePropafenoneMoricizineNa+ channel block (slow)IIBeta-blockersCarvedilolPropranololEsmololTimololMetoprololAtenololBisoprololNebivololBeta blockingPropranolol also shows some class I actionIIIAmiodaroneSotalolIbutilideDofetilideDronedaroneE-4031VernakalantK+ channel blocker Sotalol is also a beta blocker[4] Amiodarone has Class III mostly, but also I, II, & IV act...
【評論主題】59 下列化合物中，何者口服最易造成腸胃不適？(A)Erythromycin(B)Clarithromycin(C)Azithromycin(D)Dirithromycin
【評論內容】
Adverse effects of Erythromycin: Common: Gastrointestinal — Diarrhea, Loss of appetite, Nausea, Stomach cramps, Vomiting
【評論主題】74 下列何者為 antimetabolite 之抗癌藥物？(A)Methotrexate(B)Uracil mustard(C)Vincristine(D)Bleomycin
【評論內容】
(A)Methotrexate：抑制葉酸合成
(B)Uracil mustard ：Alkylating agent
(C)Vincristine ：抑制微管
(D)Bleomycin：Breaks DNA
【評論主題】67 下列何者屬於dihydropyridine 類鈣離子阻斷劑？(A)Verapamil(B)Bepridil(C)Nifedipine(D)Diltiazem
【評論內容】
Dihydropiridine：-dipine
【評論主題】67 下列何者屬於dihydropyridine 類鈣離子阻斷劑？(A)Verapamil(B)Bepridil(C)Nifedipine(D)Diltiazem
【評論內容】
Dihydropiridine：-dipine
【評論主題】74 甲醇中毒（Methanol intoxication）時，可以以靜脈注射下列何種藥物來延緩甲醇的毒性代謝產物產生？(A)異丙醇（Isopropanol） (B)乙醇（Ethanol）(C)乙烯乙
【評論內容】
乙醇會與甲醇競爭代謝酵素
【評論主題】49 下列何者不是Adrenocorticosteroids 常見之副作用？(A) Cushing 症候群 (B)低血糖 (C)骨質疏鬆症 (D)傷口癒合變慢
【評論內容】
Cushing’s syndrome arises from the repeated hypersecretion of glucocorticoids.
Some symptoms of an individual with Cushing's syndrome include low tissue protein levels, due to muscle and bone atrophy, and high blood glucose levels.
【評論主題】3 下列何種配醣體屬於S-glycoside？(A) Sinigrin (B) Prunasin (C) Ginsenoside Rg1 (D) Glycyrrhizin
【評論內容】
(A) Sinigrin：S(B) Prunasin、(C) Ginsenoside Rg1、(D) Glycyrrhizin：O
【評論主題】24 矽膠（Silica gel）為薄層層析法常用之固定相，其分析物之 R f 值大小，取決於矽膠上何種官能基與分析物作用之程度？(A)胺基(B)醛基(C)酮基(D)氫氧基
【評論內容】矽膠結構：矽膠為極性固定相，.....看...
【評論主題】28 下列何者可以與毒素（Toxins）結合保護消化道？(A)Pectin(B)Agar(C)Amylose(D)Acacia
【評論內容】Pectin is an adsorbe☆☆ ☆☆☆ ☆☆☆☆...
【評論主題】31 HMG-CoA reductase 與下列那一種化合物之生合成有關係？(A)Steroid(B)Cardiac glycoside(C)Insulin(D)Thyroid hormone
【評論內容】Acetyl-CoA➡️HMG-CoA➡️Meva.....看完整詳解
【評論主題】1 下列那個藥物常與Methotrexate 合用以減少抗癌藥的毒性？(A)Folic acid(B)Leucoverin(C)Nicotinic acid(D)Nicotinamide
【評論內容】
Methotraxate 抑制folic acid 活化
Leucoverin 為folic acid活化態
【評論主題】67 下列何者屬於dihydropyridine 類鈣離子阻斷劑？(A)Verapamil(B)Bepridil(C)Nifedipine(D)Diltiazem
【評論內容】
Dihydropiridine：-dipine
【評論主題】1 下列那個藥物常與Methotrexate 合用以減少抗癌藥的毒性？(A)Folic acid(B)Leucoverin(C)Nicotinic acid(D)Nicotinamide
【評論內容】
Methotraxate 抑制folic acid 活化
Leucoverin 為folic acid活化態
【評論主題】53 下列何者為Coronary vasodilator 且為第四型抗心律不整藥物？(A)Propranolol(B)Sotalol(C)Verapamil(D)Procainamide
【評論內容】ClassKnown asExamplesMechanismIaFast-channel blockersQuinidineAjmalineProcainamideDisopyramideNa+channel block and K+ channel blocking effectIbLidocainePhenytoinMexiletineTocainideNa+ channel block (fast)IcEncainideFlecainidePropafenoneMoricizineNa+ channel block (slow)IIBeta-blockersCarvedilolPropranololEsmololTimololMetoprololAtenololBisoprololNebivololBeta blockingPropranolol also shows some class I actionIIIAmiodaroneSotalolIbutilideDofetilideDronedaroneE-4031VernakalantK+ channel blocker Sotalol is also a beta blocker[4] Amiodarone has Class III mostly, but also I, II, & IV act...
【評論主題】59 下列化合物中，何者口服最易造成腸胃不適？(A)Erythromycin(B)Clarithromycin(C)Azithromycin(D)Dirithromycin
【評論內容】
Adverse effects of Erythromycin: Common: Gastrointestinal — Diarrhea, Loss of appetite, Nausea, Stomach cramps, Vomiting
【評論主題】74 下列何者為 antimetabolite 之抗癌藥物？(A)Methotrexate(B)Uracil mustard(C)Vincristine(D)Bleomycin
【評論內容】
(A)Methotrexate：抑制葉酸合成
(B)Uracil mustard ：Alkylating agent
(C)Vincristine ：抑制微管
(D)Bleomycin：Breaks DNA
【評論主題】61 下列何者與cyclosporine 併用時，會因為抑制其代謝而使腎毒性增加？(A)Verapamil(B)Carbamazepine(C)Chloramphenicol(D)Cimetidine
【評論內容】Cyclosporine: CYP3A4 ...
【評論主題】67 下列何者屬於dihydropyridine 類鈣離子阻斷劑？(A)Verapamil(B)Bepridil(C)Nifedipine(D)Diltiazem
【評論內容】
Dihydropiridine：-dipine
【評論主題】5 下列何者為用於癌症治療之抗生素？(A)Mitomycin C(B)Amphotericin(C)Cephalexin(D)Lincomycin
【評論內容】
Amphotericin: Amphotericin B, antifungal
【評論主題】3 利用 LAL test 是進行注射劑何項品質之控管試驗？(A)滅菌試驗(B)熱原試驗(C)裂隙試驗(D)澄明度試驗
【評論內容】
Limulus amebocyte lysate (LAL) : 鱟試劑
【評論主題】42 下列何種抗高血壓藥物最易產生姿態性低血壓的副作用？(A)ACE 抑制劑(B)選擇性β1 -接受體拮抗劑(C)α-接受體拮抗劑(D)鈣離子通道阻斷劑
【評論內容】
Clonidine (alpha-2 antagonist) 常有姿勢性低血壓副作用。
【評論主題】65 下列何者可用來治療心絞痛及氣喘？(A)Chicoric acid(B)Methoxsalen(C)Silybin(D)Khellin
【評論內容】
Khellin has been used as an herbal folk medicine, to treat a variety of maladies including: renal colic腎絞痛, kidney stones, coronary disease, bronchial asthma.
【評論主題】50 下列那一個藥品可抑制5α-reductase 而降低dihydrotestosterone 之量，在臨床上可用於治療男性良性前列腺肥大？(A)Dienestrol(B)Norgestrel(C)
【評論內容】
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. (-steride)
【評論主題】45 下列何種藥物會和microtubule 結合，促使tubulin 之polymerization，而抑制細胞分裂？(A)Doxorubicin(B)Topotecan(C)Paclitaxel(
【評論內容】
(A)Doxorubicin : inhibits the progression of topoisomerase II (DNA transcription)(B)Topotecan : Topotecan is a semi-synthetic derivative of camptothecin. (Topo I)(C)Paclitaxel : paclitaxel stabilizes the microtubule polymer. This blocks the progression of mitosis(D)Bleomycin : induction of DNA strand breaks
【評論主題】45 下列何者為標定0.1N 氫氧化鈉及0.1N 過氯酸所用的一次標準品（primary standard）？(A)三氧化二砷（Arsenic trioxide）(B)苯二甲酸氫鉀（Potassium
【評論內容】
(B)苯二甲酸氫鉀Potassium biphthalate 為一級標準品，用以滴定：NaOH、KOH、HClO4、NaB(C6H4)4
(A)三氧化二砷（Arsenic trioxide）：Ce(SO4)2、Iodine solution
(D)苯甲酸（Benzoic acid）：Sodium methoxide
【評論主題】68 下列那一個藥品屬於carbonic anhydrase inhibitor 可用於治療青光眼（glaucoma）？(A)Furosemide(B)Methazolamide(C)Bumetani
【評論內容】
azolamide
【評論主題】31 屬於selective serotonin re-uptake inhibitor 之臨床用藥為：(A)chloropromazine(B)oxazepam(C)imipramine(D)flu
【評論內容】
SSRI：Fluoxetine、Paroxetine、Sertraline、Fluvoxamine、Citalopram
【評論主題】54 過量使用Cinchona 所造成的毒性會影響到下列那一種感覺？(A)觸覺(B)聽覺(C)味覺(D)嗅覺
【評論內容】cinchona 過量：下痢、視覺、聽覺損害
【評論主題】38 具有mu agonist 作用之臨床止瀉劑為：(A)loperamide(B)nalbuphine(C) pentazocine(D)oripoxyphene
【評論內容】
(B)nalbuphine (C)pentazocine (D)oripoxyphene
為鴉片類止痛藥
【評論主題】34 具有5α-reductase inhibitor 作用之類固醇藥物為：(A)RU-486(B)clomiphene(C)danazol(D)finasteride
【評論內容】
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. (-steride)
【評論主題】60 丁香油(Clove oil)之主成分為：(A)Anethole(B)Eugenol(C)Myristicin(D)Cinnamaldehyde
【評論內容】
(A)Anethole : 洋茴香
(B)Eugenol : 丁香酚
(C)Myristicin : 肉豆蔻
(D)Cinnamaldehyde : 桂皮
【評論主題】5 下面有關蔗糖糖漿劑安定性之敘述，何者正確？(A)水解時形成兩個葡萄糖(B)水解時形成兩個果糖(C)易形成轉化糖降低甜度(D)在酸性下易焦糖化反應
【評論內容】
轉化糖是用稀酸或酶對蔗糖作用後所得含等量的葡萄糖和果糖的混合物。
【評論主題】68 關於藥物中毒的敘述，下列何者正確？(A)乙醇在中毒的濃度下以一級反應代謝(B)高劑量的 barbiturates 中毒所引起呼吸抑制作用，可以用乙醇治療(C)disulfiram 會抑制乙醛轉化
【評論內容】
Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, causing many of the effects of a hangover to be felt immediately following alcohol consumption. (使人一喝酒馬上感到不適)
【評論主題】66.下列類固醇何者抗炎作用最強？(A)Cortisone(B)Dexamethasone(C)Hydrocortisone(D)Prednisolone
【評論內容】
Glucocortico☆☆：★★★
...
【評論主題】61 薄荷油(oleum menthae)主要存在於：(A)非腺毛(B)腺毛(C)表皮細胞(D)氣孔
【評論內容】薄荷，.....看完整詳...
【評論主題】54 所謂“Bathochromic shift＂是指化合物吸光情況發生下列何種改變而言？(A)吸收峰波長向長波長處移動(B)吸收峰波長向短波長處移動(C)吸收強度增加(D)吸收強度減弱
【評論內容】Bathochromic shift= ☆☆☆ ☆☆☆☆☆, ...
【評論主題】8 下列何種抗生素之作用機轉主要不是抑制細胞壁？(A) Penicillins (B) Cephalosporins (C) Erythromycin (D) Vancomycin
【評論內容】
Macrolides: -thromycin
【評論主題】5 下列何藥物之代謝反應不屬於 phase Ⅱ反應？(A) Glycine conjugation (B) Acetyl CoA 參與之 Acetylation(C) S-adenosyl-methi
【評論內容】
Phase II metabolism
【評論主題】40 下列那一種利尿劑最易引起聽覺障礙？(A) Ethacrynic acid (B) Acetazolamide (C) Dichlorphenamide (D) Isosorbide
【評論內容】
Ototoxicity (damage to the inner ear) is a serious, but rare ADR associated with use of loop diuretics.
Examples of loop diuretics:
FurosemideBumetanideEthacrynic acidTorsemide【評論主題】19 下列心肌收縮劑（inotropic agent），何者是 phosphodiesterase Ⅲ的抑制劑？(A) Dobutamine (B) Digoxigenin (C) Milrinone
【評論內容】(A) Dobutamine : beta 1 agonist(B) Digoxigenin (C) Milrinone : inhibits the action of phosphodiesterase-3 and thus prevents degradation of cAMP(D) Ouabain : inhibiting the Na⁺/K⁺-ATPase sodium-potassium ion pump
【評論主題】62 Prazosin、terazosin 與 doxazosin 之共同基本骨架為下列何者？(A) Isoquinoline (B) Naphathalene (C) Phthalazine (D)
【評論內容】
Quinazoline
【評論主題】21 下列那一種降血壓藥物最有可能在不影響血壓之情況下，減少糖尿病人之蛋白尿及減緩腎臟病之惡化？(A) Minoxidil (B) Hydralazine (C) Enalapril (D) Doxa
【評論內容】藥物治療學：糖尿病人降血.....看完整詳解
【評論主題】27.下列那一種安眠藥（Hypnotics）其排除半衰期（half-life）最長？(A)Eszopiclone(B)Estazolam(C)Flurazepam(D)Zolpidem
【評論內容】
Elimination half-☆☆☆☆
(☆)...
【評論主題】34 下列有關Amphetamine 衍生物Methylphenidate 的敘述，何者錯誤？(A)可以用來治療發作性睡病（Narcolepsy）(B)可以用來改善注意力不集中症候群（Attentio
【評論內容】
methylphenidate common side effect: weight lost
【評論主題】72 Dimenhydrinate 是由下列何者與 8-chlorotheophylline 所形成之鹽類？(A)Tripelennamine (B)Diphenhydramine (C)Methap
【評論內容】
DiphenhydramineDimenhydranate: Chlorotheophylline
【評論主題】9 Sulfadoxine 抗菌之機轉為：(A)抑制細胞壁合成 (B)抑制蛋白質合成(C)和 p-aminobenzoic acid 競爭而抑制 DNA 合成 (D)抑制 RNA polymerase
【評論內容】
Sulfanilamide functions by competitively inhibiting (that is, by acting as a substrate analogue) enzymatic reactions involving para-aminobenzoic acid (PABA).PABA is needed in enzymatic reactions that produce folic acid, which acts as a coenzyme in the synthesis of purines and pyrimidines.
【評論主題】35.下列藥物的配對中，何者不易產生交互依賴性？(A)Morphine和Heroin(B)Ketamine和Phencyclidine(C)LSD和Psilocybin(D)Caffeine和Nico
【評論內容】
(B)Ketamine和Phenc☆☆☆☆☆☆☆☆ : ...
【評論主題】36 那一種藥物可用來治療尿崩症？(A) Vasopressin (B) Spironolactone (C) Furosemide (D) Acetazolamide
【評論內容】
尿崩症（diabetes insipindus）是指血管加壓素（vasopressin,VP）又稱抗利尿激素（antidiuretic hormone,ADH） 分泌不足（又稱中樞性或垂體性尿崩症），或腎臟對血管加壓素反應缺陷（又稱腎性尿崩症）而引起的一症候群群
【評論主題】28 下列何種 TLC 顯色劑能使皮質類固醇在白色背景產生藍色的點且相當專一？(A) Alkaline Tetrazolium blue (B) Aniline phthalate (C) Diphe
【評論內容】
TLC
胺類及Amino a☆☆☆☆: ...【評論主題】16 螢光光度法可測定溶液中 peptide 藥物之穩定性，其測定之結構中含有何種胺基酸？(A) Alanine (B) Arginine (C) Histidine (D) Tyrosine
【評論內容】
Tyrosine tryptoph...
【評論主題】31 下列有關 Van Deemter 方程式 HETP = A + B/μ + Cμ之敘述，何者錯誤？(A) HETP 值越大越佳 (B) A 為 eddy diffusion 係數(C)μ為移動相
【評論內容】
Where
HETP = a measure of the resolving power of the column [m]A = Eddy-diffusion parameter, related to channeling through a non-ideal packing [m]B = diffusion coefficient of the eluting particles in the longitudinal direction, resulting in dispersion [m2 s−1]C = Resistance to mass transfer coefficient of the analyte between mobile and stationary phase [s]u = Linear Velocity [m s−1...【評論主題】25 Phenol 在下列何種溶液中會出現 bathochromic shift？(A)NaOHaq (B)HClaq (C)甲醇 (D)甲苯
【評論內容】
bathochromic shift -->紅移-->波長大-->能量低-->安定-->Phenol(弱酸)於鹼中
【評論主題】49 有機光譜分析在 3200 cm -1有強烈吸收之官能基，可能為：① OH ② C＝C ③ C＝O ④ C ≡ C(A)① (B)②③ (C)③④ (D)①④
【評論內容】
C-C: 1000~1500
☆=☆: 1500~2000
☆★☆: 2...
【評論主題】44 有關紫外光區之輻射能與分子交互作用之敘述，下列何者錯誤？(A)紫外光圖譜並非線性吸收，因涵蓋了電子遷移（electronic transition）、轉動遷移（rotational transi
【評論內容】
(C)有n及π電子遷移：n→π、π→π*、n→σ*(少數)
【評論主題】48.下列那一種注射用水在USP要求標示「不得用於新生兒」之警語 ？(A)water for injection(B)sterile water for injection(C)bacteriosta
【評論內容】C有防腐劑
【評論主題】24在臨床上，下列那一抗生素需與cilastatin合用？(A) thienamycin(B) imipenem(C) aztreonam(D) sulbactam
【評論內容】
Imipenem/cilastatin, sold under the brand name Primaxin among others, is an antibiotic useful for the treatment of a number of bacterial infections.
Imipenem is an intravenous β-lactam antibiotic
Cilastatin inhibits the human enzyme dehydropeptidase.
【評論主題】45.下列何種膠體可吸附毒素而常出現在抗腹瀉配方（antidiarrheal formulations）中？(A)Guar gum(B)Locus bean gum(C)Xanthan gum(D)P
【評論內容】
Kaolin-Pectin : 止瀉藥
【評論主題】65 下列何者可用來治療心絞痛及氣喘？(A)Chicoric acid(B)Methoxsalen(C)Silybin(D)Khellin
【評論內容】
Khellin has been used as an herbal folk medicine, to treat a variety of maladies including: renal colic腎絞痛, kidney stones, coronary disease, bronchial asthma.
【評論主題】50 下列那一個藥品可抑制5α-reductase 而降低dihydrotestosterone 之量，在臨床上可用於治療男性良性前列腺肥大？(A)Dienestrol(B)Norgestrel(C)
【評論內容】
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. (-steride)
【評論主題】45 下列何者為標定0.1N 氫氧化鈉及0.1N 過氯酸所用的一次標準品（primary standard）？(A)三氧化二砷（Arsenic trioxide）(B)苯二甲酸氫鉀（Potassium
【評論內容】
(B)苯二甲酸氫鉀Potassium biphthalate 為一級標準品，用以滴定：NaOH、KOH、HClO4、NaB(C6H4)4
(A)三氧化二砷（Arsenic trioxide）：Ce(SO4)2、Iodine solution
(D)苯甲酸（Benzoic acid）：Sodium methoxide
【評論主題】60 丁香油(Clove oil)之主成分為：(A)Anethole(B)Eugenol(C)Myristicin(D)Cinnamaldehyde
【評論內容】
(A)Anethole : 洋茴香
(B)Eugenol : 丁香酚
(C)Myristicin : 肉豆蔻
(D)Cinnamaldehyde : 桂皮
【評論主題】54 所謂“Bathochromic shift＂是指化合物吸光情況發生下列何種改變而言？(A)吸收峰波長向長波長處移動(B)吸收峰波長向短波長處移動(C)吸收強度增加(D)吸收強度減弱
【評論內容】
Bathochromic shift= Red shift, 波長變長
Hypsochromic shift= Blue shift, 波長變短
Hyperchromic effect=增色, 吸光度上升
Hypochromic effect= 減色, 吸光度下降
【評論主題】34 下列有關Amphetamine 衍生物Methylphenidate 的敘述，何者錯誤？(A)可以用來治療發作性睡病（Narcolepsy）(B)可以用來改善注意力不集中症候群（Attentio
【評論內容】
methylphenidate common side effect: weight lost
【評論主題】35.下列藥物的配對中，何者不易產生交互依賴性？(A)Morphine和Heroin(B)Ketamine和Phencyclidine(C)LSD和Psilocybin(D)Caffeine和Nico
【評論內容】
(B)Ketamine和Phencyclidine : NMDA receptor antagonists
(C)LSD和Psilocybin : serotonin receptor agonists
(D)Caffeine和Nicotine : adenosine antagonist/ nicotinic acetylcholine receptor agonist
【評論主題】76 Pausinystalia yohimbe 樹皮所含之生物鹼，主要是屬於那一類化學結構？(A) Quinoline (B) Piperidine (C) Indole (D) Imidazole
【評論內容】
Indole:
Yohimbine: Indole alkaloids: Rauwolfi (reserpine), yohimbine, Nux vomica (strychine), physostigma, cantharanthus (vinblastine, vincristine), ergot
【評論主題】26 下列何者是 ezetimibe 之主要作用機轉？(A)抑制膽固醇之合成 (B)增加三酸甘油脂之分解(C)抑制小腸對膽固醇之吸收 (D)抑制脂肪細胞內之脂肪分解
【評論內容】
Ezetimibe works by decreasing cholesterol absorption in the intestines
【評論主題】65 下列何者可用來治療心絞痛及氣喘？(A)Chicoric acid(B)Methoxsalen(C)Silybin(D)Khellin
【評論內容】
Khellin has been used as an herbal folk medicine, to treat a variety of maladies including: renal colic腎絞痛, kidney stones, coronary disease, bronchial asthma.
【評論主題】26 下列何者是 ezetimibe 之主要作用機轉？(A)抑制膽固醇之合成 (B)增加三酸甘油脂之分解(C)抑制小腸對膽固醇之吸收 (D)抑制脂肪細胞內之脂肪分解
【評論內容】
Ezetimibe works by decreasing cholesterol absorption in the intestines
【評論主題】64使用Disulfiram戒酒時，若再喝酒，則會有噁心，嘔吐，頭痛等症狀，其原因是：(A)Disulfiram本身的毒性(B)血中Alcohol濃度增加(C)血中Acetate濃度增加(D)血中Ac
【評論內容】
Disulfiram blocks alcohol metabolism by blocking acetaldehyde dehydrogenase
【評論主題】49 下列何者不是Adrenocorticosteroids 常見之副作用？(A) Cushing 症候群 (B)低血糖 (C)骨質疏鬆症 (D)傷口癒合變慢
【評論內容】
Cushing’s syndrome arises from the repeated hypersecretion of glucocorticoids.
Some symptoms of an individual with Cushing's syndrome include low tissue protein levels, due to muscle and bone atrophy, and high blood glucose levels.
【評論主題】28 下列何者可以與毒素（Toxins）結合保護消化道？(A)Pectin(B)Agar(C)Amylose(D)Acacia
【評論內容】
Pectin is an adsorbent and bulk-forming agent and is used for the management of diarrhoea, constipation, and obesity. (Micromedex)
【評論主題】31 HMG-CoA reductase 與下列那一種化合物之生合成有關係？(A)Steroid(B)Cardiac glycoside(C)Insulin(D)Thyroid hormone
【評論內容】Acetyl-CoA➡️HMG-CoA➡️Mevalonate➡️ Sterol ➡️Steroid
【評論主題】59 下列化合物中，何者口服最易造成腸胃不適？(A)Erythromycin(B)Clarithromycin(C)Azithromycin(D)Dirithromycin
【評論內容】
Adverse effects of Erythromycin: Common: Gastrointestinal — Diarrhea, Loss of appetite, Nausea, Stomach cramps, Vomiting
【評論主題】34 具有5α-reductase inhibitor 作用之類固醇藥物為：(A)RU-486(B)clomiphene(C)danazol(D)finasteride
【評論內容】
5α-Reductase inhibitors (5-ARIs), also known as dihydrotestosterone (DHT) blockers, are a class of medications with antiandrogenic effects which are used primarily in the treatment of enlarged prostate and scalp hair loss. (-steride)