問題詳情

70 黃小姐為急性骨髓性白血病(acute myelogenous leukemia)之病患,尿酸值28 mg/dL,肌酸酐值2.6 mg/dL,診斷有腫瘤分解症狀(tumor lysis syndrome),下列何者最適合治療她的高尿酸血症?
(A) probenecid
(B) colchicine
(C) allopurinol
(D) indomethacin

參考答案

答案:C
難度:適中0.634454
統計:A(27),B(20),C(151),D(5),E(0)

用户評論

Bryan】評論

allopurinol 是一種xanthin oxidase inhibitor,能抑制uric acid的合成,是治療chemothrapy-induced hyperuiemia的最佳用藥

毛茛葛格】評論

Allopurinol在藥理上是抑制Xanthine oxidase,減少尿酸的製造。Probenecid在藥理上是抑制腎小管對尿酸的再吸收(抑制對尿酸再吸收的運輸蛋白)

高分過】評論

The management of tumor lysis syndrome, other than hydration and alkalinization, necessitates the administration of drugs to correct metabolic disturbances. Use of these medications should be instituted before the start of chemotherapy; the goal is to achieve optimal metabolic stability. Medications can be adjusted after the start of chemotherapy in response to the level of tumor lysis and/or metabolic disturbances.Allopurinol, a xanthine oxidase inhibitor, reduces the conversion of nucleic acid byproducts to uric acid, in this way preventing urate nephropathy and subsequent oliguric renal fai...

神奇地瓜泥】評論

allopurinol 只能預防不能治療不是嗎...還是又是年代的差異ಠ_ಠ