【用戶】Bryan
【年級】國三上
【評論內容】Irinotecan is a drug used for the treatment of cancer. Piperidine is an organic compound with the molecular formula5NH.
【用戶】所得皆所愿
【年級】大三上
【評論內容】Podophyllotoxin 鬼臼毒素衍生物:抑制Topo II(作用於S-G2期)(A)Etoposide(γ-lactone):睪丸癌(B)Teniposide(Thiophene):兒童急性淋巴性白血病 AMLCamptothecins 喜樹鹼衍生物:抑制Topo I(作用於G2-M期)(C)Topotecan(二甲基胺):轉移性卵巢癌、SCLC 小細胞肺癌【腸胃道吸收不佳→IV】(D)Irinotecan(Piperidine):大腸直腸癌(與5-FU、Leucovorin併用)【Prodrug:代謝成活性SN-38】