問題詳情

79 下列何者屬anthracycline glycoside 構造之抗生素?
(A) bleomycin
(B) daunorubicin
(C) streptozocin
(D) tetracycline

參考答案

答案:B
難度:簡單0.715942
統計:A(24),B(247),C(22),D(52),E(0)

用户評論

【用戶】Bryan

【年級】國三上

【評論內容】Daunorubicin or daunomycin is chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer. It is most commonly used to treat specific types of leukemia. It was initially isolated from Streptomyces peucetius.

【用戶】Bryan

【年級】國三上

【評論內容】Anthracyclines are a class of drugs used in cancer chemotherapy derived from Streptomyces bacterium Streptomyces peucetius var. caesius.

【用戶】chaochao.hsie

【年級】高三上

【評論內容】Doxorubicin  Epirubicin Daunorubicin Idarubicin Valrubicin Mitoxantrone

【用戶】一臉厭世讀國考

【年級】大一上

【評論內容】字尾有-rubicin的都是Anthracycline glycoside構造

【用戶】所得皆所愿

【年級】大三上

【評論內容】Anthracycline:經還原酶形成Hydroquinone+超氧離子> 結構:胺醣類、O-glycoside、C7-L-daunosamine、Fe2+螯合C11、12> 嵌入DNA,抑制Topo II> Hydroquinone產自由基(Doxorubicinol→心毒性)Doxorubicin(小紅莓)廣泛:治乳癌、肺癌、急性白血病(淋巴性ALL、骨髓性AML)Daunorubicin(C14少一個OH)治急性白血病(ALL、AML)Idarubicin(C1少OCH3)治急性骨髓性白血病AMLEpirubicin治乳癌> 副作用:不可逆的劑量依賴心毒性、嚴重掉髮、紅色尿液(Quinone代謝)***心臟毒性:Daunorubicin、Doxorubicin > Idarubicin、Epirubici...