問題詳情

58.關於testosterone replacement regimens的副作用,下列何者錯誤?
(A)prostate enlargement
(B)decreased libido
(C)gynecomastia
(D)sodium and water retention

參考答案

答案:B
難度:適中0.433
書單:沒有書單,新增

用户評論

吳富豪】評論

想一下testosterone會有什麼效果或副作用Testosterone therapy (TTh) may increase the risk for benign prostatic hypertrophy (BPH) and/or prostate carcinomagynecomastia (1% to 3%)electrolyte disorder (calcium, chloride, nitrogen, phosphorus, potassium, sodium)fluid retention覺得答案有一點點小bug  看看以下2大資料庫都是這樣說直覺上是缺少雄性賀爾蒙會減低性欲沒錯(補充/取代療法會增加)→postmarketing data 也是increased libido但是在副作用的欄位裡確實有decreased libido (1% to 3%) Up to dateMicromedexReduced libidoAdult Clinical Trials1) Replacement therapy (topical route): 2% or less

IG:Pharmabook】評論

選項解析10th pharmacotherapy p.3687(B)estosterone replacement 可改善性慾 (libido) In so doing, testosterone replacement regimens correct symptoms of hypogonadism, which include malaise, loss of muscle strength, depressed mood, and decreased libidoTestosterone replacement regimens do not directly correct erectile dysfunction; instead, they improve libido, thereby correcting secondary erectile dysfunction (C)會發生男性女乳症(Gynecomastia):因testosterone轉換成estrogenGynecomastia can occur as a result of conversion of testosterone to estrogen in peripheral tissues.This has been reported most often in patients with liver cirrhosis or those who are obese. (D)會造成鈉水滯留,導致肥胖、惡化高血壓、惡化心衰竭、水腫Testosterone replacement regimens can cause sodium retention, which can lead to weight gain, or exacerbate hypertension, congestive heart failure, and edema

dd5252011】評論

來源: DiPiro's Pharmacotherapy: A Pathophysiologic Approach, 12th Edition副作用:鈉水滯留、高血脂、細胞增多症、gynecomastia男性女乳症、增加性慾libido、oligospermiag少精症、肝毒性、靜脈栓塞、prostate enlargement前列腺增生